Tinuvin 770 fda

Tinuvin 770 fda. Substance identity Substance identity. Individuals are also reporting an odor similar to ﬁsh, bug spray, or chlorine. In vitro studies show that it is an L-type Ca 2+ channel and neuronal nicotic acethylcholine receptor blocker. Renowned for its exceptional attributes, this product ensures good gloss retention, compatibility, crack resistance, and thermal resistance. U. 7a17dfcf3c9e5640. Individuals are reporting a harsh taste, coughing, vomiting, and blurry vision after injection. css"> <link rel="stylesheet" href="wxp-core Tinuvin 770 Tinuvin 770DF Tinuvin 770LS UV-770 Viosorb 04 bis-TMPS (Acronym for bis(2,2,6,6-tetramethyl-4-piperidyl) sebacate) Compositions Boundary Composition Tinuvin 770 DF Revision date : 2015/12/16 Page: 2/12 Version: 4. The substance identifiers displayed in the InfoCard are the best available substance name, EC number, CAS number and/or the molecular and structural formulas. , Tinuvin 326, Chimassorb 81, Tinuvin 770, and Chimassorb 944 on ethylene-octene copolymer. [1] In 2024 it was detected as an adulterant in illicitly sold fentanyl in the United States. Files are available under licenses specified on their description page. 040 RM17 Butyl stearate 123 -95 -5 0. 10% and 1. Feb 14, 2017 · Liu et al. It is a component of many plastic materials used in medical and food industries. Sci. Obtained LODs and LOQs were 3. Acad. >Tinuvin P has FDA approval for use in a wide variety of food contact applications. Good long-term performance. 196 0. 230 RM94 Octrizole 3147-75-9 0. TINUVIN performance additives for UV protection and durability are designed to protect and extend the lifetime of coatings. 575 0. Organic coatings and inks with aesthetical, protective, and other functional properties are exposed to a variety of environmental and artificial factors such as solar radiation, humidity, temperature change, microbiological attack, air pollutants, and many more. Tinuvin® 770 offers broad compatibility and can be easily dispersed. Tinuvin 770 DF Revision date : 2021/07/07 Page: 1/12 Version: 6. g. 317 RM92 Benzophenone-1 131-56-6 below DL below DL 0. 296 0. hals 123 / light stabilizer 123 / tinuvin 123: 129757-67-1: hals 622 / light stabilizer 622 / tinuvin 622: 65447-77-0: hals 770 / light stabilizer 770 / tinuvin 770: 52829-07-9: hals 783 / uv light stabilizer 783 / tinuvin 783: hals 791 / light stabilizer 791 / tinuvin 791: hals 944 light stabilizer-944 chimasorb 944: 70624-18-9 / 71878-19-8 Here, bis(2,2,6,6-tetramethyl-4-piperidyl) sebacate (marketed under the name Tinuvin 770) is identified as a major contaminant in applications using liquid chromatography coupled with mass spectrometry (LC-MS). The TINUVIN 5000 series and other TINUVIN blends offer synergistic combinations of UVA and HALS technology against surface defects while also bolstering color and gloss retention Bis (2,2,6,6-tetramethyl-4-piperidinyl) sebacate (BTMPS; Tinuvin 770), a sterically hindered amine light and radiation stabilizer manufactured by Ciba-Geigy Corp. Read more related scholarly scientific articles and abstracts. Food and Drug Administration, 10903 New Hampshire Ave, Silver Spring, MD 20993-0002 U. Tinuvin 770 [bis(2,2,6,6-tetramethyl-4-piperidinyl) sebacate], is a UV light stabilizer plastic additive used worldwide. <link rel="stylesheet" href="grid-angular. 1の販売業者や製造者からTinuvin® 770を購入できます。 Oct 10, 1993 · This compound is identical to Tinuvin 770, which is used worldwide as a light stabilizer for polyolefins. 035 RM93 Tinuvin P 2440-22-4 0. Some additives absorb these energy packets, which means that the polymer itself doesn’t have to, other scavenge radicals generated by the high energy packets, preventing deterioration of the polymer. Tetramethyl piperidine derivative . 83 and 2. 4 mg/L for Tinuvin 770 and 0. 723 May 1, 2005 · Tinuvin 770 (BTMPS) is a non-competitive, use-dependent antagonist of nicotinic acetylcholine receptors (nAChRs). 401 0. Feb 1, 1994 · Bis (2,2,6,6-tetramethyl-4-piperidinyl) sebacate (BTMPS; Tinuvin 770), a sterically hindered amine light and radiation stabilizer manufactured by Ciba-Geigy Corp. It has been developed especially for high solids, acid catalyzed automotive and industrial coatings, such as two-coat metallic thermosetting acrylate systems or one-coat opaque thermosetting acrylate and polyester coatings. (Summit, NJ) and used in a wide range of plastics, inhibits nicotinic acetylcholine receptors expressed in Xenopus oocytes in a use-depen … Mar 28, 2019 · The first case of allergic contact dermatitis caused by Tinuvin 770 is reported, which is reported to be the first case in the world of its kind. Description: BTMPS, also commonly referred to as bis(2,2,6,6-tetramethyl-4-piperidyl)sebacate or Tinuvin 770, is the latest substance to appear in the recreational opioid supply as an adulterant alongside fentanyl. It provides excellent light stability for thick sections but can also be used for articles with a high surface area such as films and tapes. 033 0. 0 (30546638/SDS_GEN_US/EN) Label elements Pictogram: Signal Word: Danger Hazard Statement: H318 Causes serious eye damage. 3 (30546638/SDS_GEN_US/EN) 1. The superior sensitivity of current mass spectrometers makes them prone to contamination issues, which can have deleterious effects on sample analysis. This compound (approximately 12 micrograms per tube approximately 25 nmol) blocked …. Jul 15, 2001 · Glossmann and his study group managed to extract this compound by aqueous or organic solvents from laboratory plastic tubes, and propose that Tinuvin 770 is a potent blocker of L-type Ca 2+-channel through the phenylalkylamine and benzothiazepine-selective drug binding domains of the α 1 subunit of the receptor [Proc. , manufacturing, packaging, delivery systems and devices). 220 0. It is a white crystalline powder. Tinuvin® 1577 is well suited for processing and aging conditions where high loadings, low volatility and good compatibility are required. 2 (30546638/SDS_GEN_CA/EN) 1. Sep 25, 2023 · Tinuvin® 770 is bis(2,2,6,6,-tetramethyl-4-piperidyl) sebaceate by BASF which funcions as hindered amine light stabilizer (HALS). Tinuvin® 770 is a hindered amine light stabilizer (HALS) designed for applications demanding high light stabilization. css"> <link rel="stylesheet" href="atoms-core. Our portfolio contains two types of light stabilizers: Ultraviolet Light Absorbers (UVA) and Hindered-Amine Light Stabilizers (HALS). 41 and 11. 288 0. Sep 17, 2024 · BTMPS or Tinuvin 770: an industrial chemical additive used as protection in plastics. >UV P can be used alone or in a variety of blends and combinations with antioxidants or UV absorbers where often a synergistic performance is observed. It is designed to meet durability requirements of all exterior solvent-based industrial coatings. Mar 1, 2010 · Abstract. Tinuvin®の具体的な加工情報や、Additive -- UV Protector / Light Stabilizerジェネリックファミリーの一般情報をご確認いただけます。登録またはサインイン詳細情報を確認してください。ご購入方法. Handing and Safety: >In accordance with good industrial practice, handle with care and avoid unnecessary personal contact. Tinuvin 770 is often added to laboratory and medical plastics as a UV stabilizer. 182 0. Here, bis(2,2,6,6-tetramethyl-4 Feb 18, 2004 · Detection of tinuvin 770, a light stabilizer of plastic materials from dialysis membranes, by high-performance liquid chromatographic analysis. 172 May 13, 2021 · This page was last edited on 13 May 2021, at 01:23. Jan 31, 2024 · Tinuvin® 783 FDL by BASF is a synergistic mixture of Chimassorb® 944 and Tinuvin® 622. S Tinuvin 770 DF Revision date : 2021/07/07 Page: 1/11 Version: 7. 275 RM18 Tinuvin 320 3846 -71 -7 0. Used in hotmelt, reactive, solvent-based and radiation curing adhesives and sealants. BTMPS is a known nicotinic Tinuvin® 770 is a multipurpose HALS for various solid applications like for example powder coatings or hot melt adhesives EMEA | MyIndustryWorld MyIndustryWorld Industries Products Sustainability Discover Oct 15, 1993 · Bis(2,2,6,6-tetramethyl-4-piperidyl) sebacate is classified as the prototype of another class of L-type Ca(2+)-channel blockers that binds to the alpha 1 subunit at the drug-binding domains selective for (+)-tetrandrine or (+)-cis-diltiazem. TINUVIN® 5000 series and other TINUVIN blends with UV absorber (UVA) and hindered amine light stabilizer (HALS) technology for solvent-based and aqueous formulations. (Summit, NJ) and used in a wide range of plastics, inhibits nicotinic acetylcholine receptors expressed in Xenopus oocytes in a use-dependent manner. 1M), or click on a page image below to browse page by page. Key Features & Benefits. Feb 1, 2004 · Tinuvin 770 binds to the α4,β2 acetylcholine receptors with high affinity in the central nervous system (Flores et al. A pharmacologically active agent was easily extracted by aqueous or organic solvents from laboratory plastic tubes (Falcon Blue Max) and has been TINUVIN ® 123 . 0%, depending on substrate and performance requirements of the final application. Quality parameters of UPLC-UV/Vis method were evaluated. Properties . These experiments were designed to confirm the nAChR RM16 Oleamide 301 -02-0 0. Full text Get a printable copy (PDF file) of the complete article (1. Identification Product identifier used on the label Tinuvin 770 DF Recommended use of the chemical and restriction on use Recommended use*: stabilizer Unsuitable for use: The product is not recommended to be used in contact with mucous membranes, Jul 27, 2010 · Reliable determinations of monomeric units of Chimassorb 944 and molecule of Tinuvin 770 were achieved by HPLC-ESI(+)-LTQ FT Orbitrap MS method using scan mode. Presently the ganglionic blocking drug mecamylamine is used almost exclusively to block central … Aug 1, 2024 · Hemodynamic Effects of the Light Stabilizer Tinuvin 770 in Dogs In Vivo; Contact allergy to Tinuvin 770, a hindered amine light stabilizer in sandals contributing to hyperkeratotic foot dermatitis; Contamination. H411 Toxic to aquatic life with long lasting effects. Our previous study has indicated the time-dependent nature of Tinuvin 770 cytotoxicity on isolated rat cardiomyocytes caused by altered Ca 2+ metabolism. Presently the ganglionic blocking drug mecamylamine is used almost exclusively to block central nAChRs upon peripheral administration. It is particularly well suited for LDPE, LLDPE, HDPE films, tapes and thick sections and for PP films. Journal of chromatographic science. H400 Very toxic to aquatic life. 312 0. Precautionary Statements (Prevention): P280 Wear eye/face protection. Light stabilizers are designed to protect polymers from photooxidation induced by the intense UV energy coming from the sun. Proceedings of the National Academy of Sciences of the United States of America, 90(20), 9523-9527 (1993-10-15) Tinuvin 770 [bis(2,2,6,6-tetramethyl-4-piperidinyl)sebacate] is a pharmacologically active agent used worldwide as a light stabilizer for plastic materials. by Péter Sótonyi, Anikó Kovács, Gábor Volk, Jeno Járay, András Benko. 189 0. Tinuvin® 1600 is a high performance ultraviolet light absorber of the hydroxyphenyl triazine class exhibiting very low volatility, high absorption and good compatibility with a variety of polymers, co-additives and resin compositions. Identification Product identifier used on the label Tinuvin 770 DF Recommended use of the chemical and restriction on use Recommended use*: stabilizer Unsuitable for use: The product is not recommended to be used in contact with mucous membranes, TINUVIN® and CHIMASSORB® UV absorbers (UVA) for water-based, solvent based, and solvent-free formaulations . Good thermal stability. The drug is highly lipid soluble and as such it has the potential to act within the brain. BTMPS is a symmetrical conjugate of methylated piperidines, which are themselves Oct 15, 1993 · A light stabilizer (Tinuvin 770) that elutes from polypropylene plastic tubes is a potent L-type Ca(2+)-channel blocker. H Glossmann , S Hering , A Savchenko , +6 , W Berger , K Friedrich , M L Garcia , M A Goetz , J M Liesch , D L Zink , and G J Kaczorowski -6 Authors Info & Affiliations A light stabilizer (Tinuvin 770) that elutes from polypropylene plastic tubes is a potent L-type Ca(2+)-channel blocker. Use of the information, documents and data from the ECHA website is subject to the terms and conditions of this Legal Notice, and subject to other binding limitations provided for under applicable law, the information, documents and data made available on the ECHA website may be reproduced, distributed and/or used, totally or in part, for non-commercial purposes provided that ECHA is Jan 31, 2024 · Tinuvin® 770 DF by BASF is bis(2,2,6,6,-tetramethyl-4-piperidyl) sebaceate. Key features and benefits JavaScript is disabled in your browser which limits the functionality of the website. Mass Spectrometry Contamination from Tinuvin 770, a Common Additive in Laboratory Plastics; Pharmacological effects U. H Glossmann et al. Wellt, your trusted supplier of chemical additives, is proud to offer the best-in-class Tinuvin 770, HALS 770, and Light Stabilizer 770 directly from China. Chemical Structure. Tinuvin 770 (BTMPS) is a non-competitive, use-dependent antagonist of nicotinic acetylcholine receptors (nAChRs). 295 0. Tinuvin® 1577 is an ultraviolet light absorber (UVA) designed to ensure polycarbonates and polyesters achieve a higher resistance to weathering than conventional benzotriazole UVAs. S. Food and Drug Administration , Health & Human Services Freedom of Information Act Tinuvin® 1577 is an ultraviolet light absorber (UVA) designed to ensure polycarbonates and polyesters achieve a higher resistance to weathering than conventional benzotriazole UVAs. A Tinuvin 770 is a low molecular weight hindered amine light stabilizer (HALS) for applications demanding particularly high light stability. > It has FDA approval for use in a wide variety of food contact applications. Jan 1, 2004 · Tinuvin 770 [bis(2,2,6,6-tetramethyl-4-piperidinyl)sebacate] is a pharmacologically active agent used worldwide as a light stabilizer for plastic materials. 285 RM91 Tinuvin 770 52829-07-9 0. Jul 1, 2013 · B bis(2,2,6,6-tetramethyl-4-piperidyl) sebacate (marketed under the name Tinuvin 770) is identified as a major contaminant in applications using liquid chromatography coupled with mass spectrometry (LC-MS). Good long-term performance ; Good thermal stability; Applications Tinuvin 770 DF is designed to meet durability requirements of all exterior solvent-based industrial coatings. . >The use levels range between 0. Jul 15, 2001 · Glossmann and his study group managed to extract this compound by aqueous or organic solvents from laboratory plastic tubes, and propose that Tinuvin 770 is a potent blocker of L-type Ca(2+)-channel through the phenylalkylamine and benzothiazepine-selective drug binding domains of the alpha(1) subunit of the receptor [Proc. 253 0. Tinuvin 770 (bis(2,2,6,6-tetramethyl-4-piperidyl) sebacate; BTMPS) is a hindered amine light stabilizer (HALS) used to prevent deterioration and discoloration of polymer compounds. It is a low molecular weight hindered amine light stabilizer (HALS) for applications demanding particularly high light stability. The ‘Substance identity’ section is calculated from substance identification information from all ECHA databases. Sep 3, 2024 · The following information was compiled in August 2024 and is subject to change as new research is conducted and as new information becomes available: Description: BTMPS, also commonly referred to as bis(2,2,6,6-tetramethyl-4-piperidyl)sebacate or Tinuvin 770, is the latest substance to appear in the recreational opioid supply as an adulterant 5 days ago · BTMPS (also known as Tinuvin 770) is a hindered amine light stabilizer with the chemical formula C28H52N2O4. 321882342998c065. [2][3] Tinuvin® 770 DF (ED) serves as a highly effective light stabilizer, belonging to the Hindered Amine Light Stabilizer (HALS) chemical family. 035 0. Tinuvin® 770 is a multipurpose HALS for various solid applications like for example powder coatings or hot melt adhesives EMEA | MyIndustryWorld MyIndustryWorld Industries Products Sustainability Discover Tinuvin 770 (BTMPS) is a non-competitive, use-dependent antagonist of nicotinic acetylcholine receptors (nAChRs). Earlier studies demonstrated its in vitro L-type Ca2+ channel and nicotinic acetylcholine receptor … Tinuvin 770 is a light stabilizer present in numerous polymers utilized in medical or pharmaceutical applications (e. TINUVIN 123 is a liquid hindered amine light stabilizer (HALS) based on an amino-ether functionality. In vitro studies show that it is an L-type Ca(2+) channel and neuronal nicotic acethylcholine receptor blocker. Typical Properties. Natl. They found that the UV performance of Tinuvin 770 and Chimassorb 944 was higher than that of Chimassorb 81 and the UV performance of Tinuvin 326 was the lowest. 166 RM95 Tinuvin 234 70321-86-7 0. Appearance. Oct 15, 1993 · A pharmacologically active agent was easily extracted by aqueous or organic solvents from laboratory plastic tubes (Falcon Blue Max) and has been chemically identified as bis(2,2,6,6-tetramethyl-4-piperidyl) sebacate. The drug is highly lipid soluble and as such it has the potential to act within Used as tinuvin p equivalent. Back to previous NOW DOWNLOADING Technical datasheet - TINUVIN® 770 DF If download doesn't start automatically, click here. 255 0. TINUVIN 770 DF is a solid basic hindered amine light stabilizer (HALS) developed for coating, adhesive and sealant applications. We herein report the first case of allergic contact dermatitis caused Tinuvin 770 is a low molecular weight hindered amine light stabilizer (HALS) for applications demanding particularly high light stability. 78 mg/L for Chimassorb 944, respectively. These high-performance additives will protect your products from harmful UV radiation, ensuring long-lasting durability and colorfastness. 210 0. All structured data from the file namespace is available under the Creative Commons CC0 License; all unstructured text is available under the Creative Commons Attribution-ShareAlike License; additional terms may apply. The cardiomyocytes culture, suspended in 25 nM Tinuvin 770 RM90 Tinuvin 328 25973-55-1 0. 394 0. Tinuvin 770 is a light stabilizer present in numerous polymers utilized in medical or pharmaceutical applications (e. Tinuvin 770 is a low molecular weight hindered amine light stabilizer (HALS) for applications demanding particularly high light stability. Protect skin. , 1992). Tinuvin 770 DF is a solid basic hindered amine light stabilizer (HALS) developed for coating, adhesive and sealant applications. investigated the effect of four types of UV stabilizers e. It is a versatile light stabilizer with good extraction resistance, low gas fading and low pigment interaction. eyymvro qtwm qnzkxq bmjtgfw nvy hgoot qrhwa eqxho thwty iyalcu